首页 理论教育 褐色肠综合征

褐色肠综合征

时间:2022-05-12 理论教育 版权反馈
【摘要】:褐色肠综合征很罕见,本病多见于各种原因引起的小肠吸收不良患者,可并发小肠假性肠梗阻。确切发病机制不明,有学者认为可能与长期小肠吸收不良致维生素E缺乏或平滑肌线粒体异常有关。也有病例检测到其他脂溶性维生素,如维生素A和维生素D、水溶性维生素如维生素C和维生素B1缺乏。本病的确诊依赖于组织病理检查,病理表现为小肠平滑肌细胞内有大量脂褐素沉着。

第六节 褐色肠综合征

褐色肠综合征(brown bowel syndrome)很罕见,本病多见于各种原因引起的小肠吸收不良患者,可并发小肠假性肠梗阻。确切发病机制不明,有学者认为可能与长期小肠吸收不良致维生素E缺乏或平滑肌线粒体异常有关。也有病例检测到其他脂溶性维生素,如维生素A和维生素D、水溶性维生素如维生素C和维生素B1缺乏。本病的确诊依赖于组织病理检查,病理表现为小肠平滑肌细胞内有大量脂褐素沉着。

(韩少良)

参考文献

1.王志明.胃大部切除术胃肠错误吻合的教训分析.实用外科杂志,1981,5(1):277~279

2.朱维铭.短肠综合征的治疗进展.中国实用外科杂志,2004,24(1):20~23

3.姜阳贵,姜拥武,陈哲京.胃(食管)回肠错误吻合的诊治(附11例报告).中国普通外科杂志,1998,9:384~385

4.韩少良,姚建高,张陪趁,等.胃回肠错误吻合术后并发重度营养不良1例.罕少疾病杂志,2008,15(3):55~56

5.黎介寿.成人短肠综合征的治疗进展.肠外与肠内营养,2005,12(5):257~259

6.Abu-Elmagd K,Reyes J,Todo S.Clinical intestinal transplantation:new perspectives and immunologic consider-ation.J Am Coll Surg,1998,186(5):512~525

7.Buchman AL.Etiology and initial management of short bowel syndrome.Gastroenterology,2006,130(suppl 2):S5~S15

8.Byrn TA,Persinger RL,Young IL,et al.A new treatment for patients with short-bowel syndrome:growth hor-mone,glutamine,and a modified diet.Ann Surg,1995,222:243~254

9.Byrne TA,Morrissay TB,Nattakom TV,et al.Growth hormone glutamine and modified diet enhance nutrient absorption in patients with severe short bowel syndrome.JPEN,1995,19(2):296~302

10.Cohen BR,Schapira A,Adlersberg D.A simple clue to gastroileostomy.Flat glucose tolerance test.Arch Intern Med,1962,109:660~664

11.Gong J,Zhu W,Li N,et al.Serum citrulline is a simple quantitative marker for small intestinal enterocytes mass and absorption function in short bowel patients.J Surg Res,2005,127(2):177~182

12.Grant D,Abu-Elmagd K,Reyes J,et al.2003report of the intestine transplant registry:a new era handsewed.Ann Surg,2005,241(4):607~613

13.Hielscher H,Ewert T,Gallenkamp U,et al.Acute polyneuropathy due to malabsorption syndrome following gastreileostomy.Nervenartz,1982,53(6):353~355

14.Horvakth K,Jami M,Hill A,et al.Isocaloric glutamine-free diet and the morphology and function of rat small

intestine.JPEN,1996,20:128

15.Kim HB,Lee PW,Garza J,et al.Serial transverse enteroplasty for short bowel syndrome:a case report.J Pediatr Surg,2003,38(6):881~885

16.Ladefoged K,Hessov I,Jarnum S.Nutrition in short-bowel syndrome.Scand J Gastroentrol,1996,31(suppl)216,122~131

17.Nightingale JM,Walker ER,Farthing MJ,et al.Effect of omeprazole on intestinal output in the short bowel syndrome.Aliment Pharmacol Ther,1991,5:405~412

18.Pera C,Capdevila-Torra J,Leon J.Gastroileostomy:an avoidable surgical error(report of 3cases and review of the problem).Rev Esp Enferm Apar Dig,1971,35(1):1~24

19.Reynaert H,Debeuckelaere S,de Waele B,et al.The brown bowel syndrome and gastrointestinal adenocarcino-ma.Two complications of vitamin E deficiency in celiac sprue and chronic pancreatitis.J Clin Gastroenterol,1993,16(1):48~51

20.Scolapio JS.Effect of growth hormone,glutamine,and diet on body composition in short bowel syndrome:a ran-domized,controlled study.JPEN J Parenter Enteral Nutr,1999,23:309~313

21.Sugiura T,Tashiro T,Yamamori H,et al.Effects of total parenteral nutrition on endotoxin translocation and extent of the stress response in burned rats.Nutrition,1999,15:570~575

22.Thompson JS.Management of the short bowel syndrome.Gastroenterol Clin North Am,1993,23:403~420

23.Thompson JS,Pinch LW,Young R.Long-term outcome of intestinal lengthening.Transpant Proc,2000,32(6):1242~1243

24.Washizawa N,Gu LH,Gu L,et al.Comparative effects of glucagon-like peptide-2(GLP-2),growth hormone(GH),and keratinocyte growth factor(KGF)on markers of gut adaptation after massive small bowel resection in rats.JPEN,2004,28(6):399~409

25.Weiming Z,Ning L,Jieshou L.Effect of recombinant human growth hormone and enteral nutrition on short bowel syndrome.JPEN,2004,28(6):377~381

26.Zhu WM,Li N,Li JS.Effect of recombinant human growth hormone and enteral nutrition on short bowel syn-drome.JPEN,2004,28(3):377~381

27.Zhu WM,Li N,Ren J,et al.Rehabilitation therapy for short bowel syndrome.Chin Med J,2002,115(5):776~778

28.Ziegler TR,Mantell MP,Rombeau JL,et al.Effects of glutamine and IGF-1administration on intestinal growth and IGF pathway after partial small bowel resection.JPEN,1994,18(suppl):20

免责声明:以上内容源自网络,版权归原作者所有,如有侵犯您的原创版权请告知,我们将尽快删除相关内容。

我要反馈